On April 30 th , France set up national surveillance for pediatric inflammatory multisystem syndrome (PIMS) in order to assess this emerging disease and potential associations with COVID-19. Belot et al found that 156 cases had been notified as of May 17 th and the authors classified these cases based on clinical features and SARS-CoV-2 status (79 were classified as confirmed pediatric inflammatory multisystem syndrome (CoV-PIMS), 16 as probable CoV-PIMS, 13 as possible CoV-PIMS and 48 as not related/inconclusive CoVPIMS). The authors found the peak in the epidemic curve of CoV-PIMS cases occurred 4-5 weeks after the peak of the COVID-19 epidemic, which may suggest that PIMS could be a post-infectious manifestation of COVID-19. The authors also found the geographic distribution of CoV-PIMS cases to be comparable to the geographic distribution of COVID-19 hospitalizations, based on descriptive maps. The clinical presentations differed between the CoV-PIMS cases and the non-CoV PIMS cases in median age, clinical features, and severity; the authors suggest that early recognition of CoV-PIMS is essential for effective management.