Routine childhood immunisation during the COVID-19 pandemic in Africa: a benefit-risk analysis of health benefits versus excess risk of SARS-CoV-2 infection

July 17, 2020

Abbas KM, Procter SR, van Zandvoort K, et al.

The Lancet Global Health

In this study, Abbas et al. used previous estimates of country-specific child mortality rates for vaccine-preventable diseases to model the potential effect of suspending routine childhood immunisation programs in Africa. The authors found that if vaccines for diphtheria, tetanus, pertussis, hepatitis B, H. influenzae type b, S. pneumoniae, rotavirus, measles, meningitis A, rubella and yellow fever were suspended, an estimated 84 children would die before age 5 due to the suspension for every one excess COVID-19 death attributable to SARS-CoV-2 infection acquired during routine vaccination visits. This benefit was greatest for the vaccinated child, and secondarily their siblings, parents/adult carers and surrounding older adults. Overall, authors do not recommend suspending routine childhood immunisations in Africa during the COVID-19 pandemic, as the risks of mortality from vaccine-preventable diseases, far outweigh the benefits.

Abbas KM, Procter SR, van Zandvoort K, et al. Benefit-risk analysis of health benefits of routine childhood immunisation against the excess risk of SARS-CoV-2 infections during the Covid-19 pandemic in Africa. The Lancet Global Health 2020; : 2020.05.19.20106278.

Partners