Using a retrospective, population-based methodology, the authors aimed to understand the amount of excess cerebrovascular-related mortality in the US from January to May 2020, the relationship between this mortality and emergency services use, and the effect of social distancing behaviour on excess cerebrovascular mortality. Results showed an excess of 918 cerebrovascular deaths in this time period, with greater than expected deaths occurring between March 28 and May 2. Furthermore, excess cerebrovascular deaths occurred two weeks after emergency services use started to decrease and COVID-19 related deaths were low. Weekly excess stroke-related mortality increased as COVID-19 deaths increased, EMS calls decreased, and independently, as social distancing increased and mobility decreased. These emphasize the need to create awareness for patients with stroke symptoms to utilize emergency medical services, even during a pandemic.