Bioaerosol Sampling for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Referral Center with Critically Ill Coronavirus Disease 2019 (COVID-19) Patients March–May 2020

January 28, 2021

Morgan A Lane; Erik A Brownsword; Ahmed Babiker; Jessica M Ingersoll; Jesse Waggoner; Marie Ayers; Matthew Klopman; Timothy M Uyeki; William G Lindsley; Colleen S Kraft

Clinical Infectious Diseases

Lane et al. aimed to assess the presence of SARS-CoV-2 in aerosols outside of critically ill COVID-19 patient rooms to understand better the safety concerns posed to healthcare personnel. Data was collected via National Institute for Occupational Safety and Health (NIOSH) BC 251 2-stage cyclone samplers placed at 102 cm and 152 cm above the floor throughout the nursing stations, patient room hallways, and visitor corridors of 6 intensive care units (ICUs) in a tertiary referral hospital in Atlanta, GA, USA. Samples were taken for 22 days, and the sampling period lasted 6 hours at the same time of day, which spanned the morning shift change to the next shift change. Results revealed that none of the 528 aerosol samples taken tested positive for SARS-CoV-2 RNA via reverse transcriptase polymerase chain reaction (rRT-PCR) testing. As the ICUs contained both positive and negative pressure rooms, the authors suggest that, given the lack of SARS-CoV-2 aerosols detected in the hallway, negative pressure may not be necessary to prevent viral aerosols from dispersing outside patient rooms. The authors assert that this study’s results highlight that environmental controls and personal protective equipment are important and effective at controlling the presence of SARS-CoV-2 aerosols. Tentatively, such findings provide reassurance for alternatives to the use of tight-fitting respirators outside of patient rooms.

Lane, M. A., Brownsword, E. A., Babiker, A., Ingersoll, J. M., Waggoner, J., Ayers, M., … Kraft, C. S. (2021). Bioaerosol Sampling for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Referral Center with Critically Ill Coronavirus Disease 2019 (COVID-19) Patients March–May 2020. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa1880

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