A systematic review of pregnant women with COVID-19 and their neonates
April 4, 2021
Mirbeyk, M., Saghazadeh, A. & Rezaei, N.
A systematic review was carried out in which 37 articles were included which studied 364 pregnant women with COVID-19 and 302 newborns. With a positive PCR test for the disease, mild to moderate manifestations of COVID-19 were described throughout the population. A total of 219 newborns underwent SARS-CoV-2 nasopharyngeal specimen collection, of which 11 tested positive (5%) and two reported high IgM léveles in newborns who tested negative for SARS-CoV2 . Because there is no possibility of IgM transfer across the placenta, such data suggested vertical transmission of COVID-19, however studies are required to investigate the potential for COVID-19 to be transmitted vaginally and the possible association between maternal COVID-19 infection and long-term child health. Therefore, it is concluded that despite the high rate of contagion of COVID-19 reported, the vertical transmission of this virus continues to generate uncertainty due to the lack of reported evidence.
Mirbeyk, M., Saghazadeh, A. & Rezaei, N. A systematic review of pregnant women with COVID-19 and their neonates. Arch Gynecol Obstet, 2021, 304, 5–38.