Stroke risk, phenotypes, and death in COVID-19

September 15, 2020

Sebastian Fridman, Maria Bres Bullrich, et. al

Neurology

The researchers of this study aimed to explore the characteristics of COVID-19 patients which had experiencing stroke. The aims of the study were to estimate the risk of stroke in patients who were hospitalized with COVID-19, to quantify the in-hospital mortality of COVID-19 patients which had experienced a stroke, and to analyse the risk factor profiles of young patients with COVID-19 and stroke, to derive clinical phenotypes of patients with stroke and COVID-19 and to compare the hospital mortality between the derived clinical phenotypes. A meta-analysis was conducted on 10 studies and one unpublished series. The analysis found relatively high 1.8% occurrence of stroke among hospitalized COVID-19 patients compared to patients with other viral respiratory infections. Furthermore, in hospital mortality was higher for young patients with COVID019 with stroke of any type compared to patents >70 years of age. The findings of the study illuminated the impact age, comorbid conditions and severe COVID-19 symptoms could have on the risk of death in patients.

Fridman S, Bullrich MB, Jimenez-Ruiz A, et al. Stroke risk, phenotypes, and death in COVID-19. Neurology 2020; 95: e3373–85.

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